What are the best bedtime hand creams to heal dry, cracked skin overnight?
Discover 10 proven night creams that repair your hands while you sleep—no harsh chemicals, just real results for softer mornings.
Dry, cracked hands keep you up at night. The right bedtime hand cream works while you sleep to heal and protect. Wake up to softness you can feel.
People massage it in before bed and wake with less pain, fewer cracks. Real relief builds trust fast when skin finally heals overnight.
Let this guide help you pick the perfect night cream for your hands. You’ll find clear, proven choices that repair as you rest. Ready for smoother mornings? Let’s begin.
List of Top 10 Bedtime Hand Creams
| Image | Title | Best For | Price |
|---|---|---|---|
 |
O’Keeffe’s Working Hands Night Treatment Hand Cream for Extreme Dryness – 7 oz Tube (1 Pack) – Repairing Skincare for Cracked, Dry Hands |
O'Keeffe's Working Hands Night Treatment is perfect for anyone whose hands are cracked, raw, or painfully dry—especially nurses, dishwashers, mechanics, gardeners, and frequent hand-washers. |
|
 |
O’Keeffe’s Working Hands Hand Cream for Extreme Dryness – 3 oz Travel Size Tube (1 Pack) – Repairing Skincare for Cracked, Dry Hands |
This hand cream is perfect for anyone whose hands are rough, cracked, or painfully dry—especially nurses, construction workers, mechanics, gardeners, and frequent hand-washers. If your skin feels tight, looks flaky, or stings after work, O’Keeffe’s Working Hands delivers real relief when regular lotions just won’t cut it. Keep it with you at work, in your gym bag, or by your bed—one dab transforms dry, raw skin into smooth, strong hands you can rely on. |
|
 |
Aveda Hand Relief Moisturizing Creme | Rich Hand Cream | with Andiroba Oil, 1.3 Fl Oz |
Dry, cracked hands? This cream is perfect for you. |
|
 |
O’Keeffe’s Working Hands Hand Cream for Extreme Dryness – 3.4 oz Jar (1 Pack) – Repairing Skincare for Cracked, Dry Hands |
O'Keeffe's Working Hands Hand Cream is perfect for anyone whose hands crack, bleed, or feel raw from hard work, harsh weather, or constant washing—think nurses, mechanics, farmers, chefs, and busy parents. If your skin feels like sandpaper, this cream locks in moisture to heal and protect, so you get real relief, fast. |
|
 |
L’Occitane Nourishing Lavender Hand Cream Enriched with Lavender Essential Oil and Shea Butter, Net Wt. 1 oz. |
This hand cream is perfect for anyone with dry or tired hands who wants quick relief. If your skin feels rough or tight after washing, it needs this soothing blend of lavender oil and shea butter. Use it daily to keep hands soft and protected, even in harsh weather. Busy hands deserve care—apply a little and feel the difference right away. Ideal for nurses, teachers, cooks, and parents who wash hands often and need lasting comfort. Gentle, effective, and deeply nourishing without greasiness. |
|
 |
O’Keeffe’s Working Hands Hand Cream for Extreme Dryness – 3 oz Tube (2 Pack) – Repairing Skincare for Cracked, Dry Hands |
O'Keeffe's Working Hands Hand Cream is perfect for anyone whose hands are rough, cracked, or painfully dry from hard work, frequent washing, or harsh weather. If you wash dishes, work outdoors, use tools, or spend hours with your hands in water or sanitizer, this cream delivers real relief fast. It’s especially trusted by nurses, mechanics, cleaners, gardeners, and builders who need their hands to feel strong again. Safe, unscented, and non-greasy, it fits right into your daily routine—guaranteed to heal what everyday life breaks. |
|
 |
eos Shea Better Hand Cream – Vanilla Cashmere Hand Lotion | Instant Hydration + Lasting Protection | 2.5 oz |
This hand cream is perfect for anyone with dry, rough hands who wants fast relief and lasting softness. If you wash your hands often or work in tough conditions, Vanilla Cashmere delivers instant hydration and 24-hour protection without grease or residue. Vegan and hypoallergenic, it’s safe for sensitive skin and packed with nourishing shea butter and oils. Whether you’re a busy nurse, a parent juggling chores, or just someone who hates dry patches, this travel-size lotion fits right into your daily routine—smooth, soothing, and seriously effective. Pamper your hands the clean, kind way: apply, feel better, repeat. |
|
 |
No7 Protect & Perfect Intense Advanced Nourishing Hand and Nail Cream – Anti Aging Hand Cream with Vitamin B5 – Contains Matrixyl 3000+ Collagen Peptide Anti Wrinkle Technology (75 ml) |
This hand cream is perfect for women who want younger-looking hands without heavy effort. If your skin feels dry or shows fine lines, it deeply moisturizes and smooths quickly. Busy moms, professionals, and skincare lovers will love how fast it absorbs and how real the results look—no greasy residue, just soft, firmer skin. Make it your daily shield against aging hands, especially if you use sanitizers often or work with your hands. Trust No7 to deliver visible improvement in just two weeks. |
|
 |
O’Keeffe’s Working Hands Hand Cream for Extreme Dryness – 7 oz Tube (1 Pack) – Repairing Skincare for Cracked, Dry Hands |
This hand cream is perfect for anyone whose hands are rough, cracked, or painfully dry. If you wash your hands constantly, work with tools, chemicals, or outdoors, or just can’t seem to heal dry skin no matter what you try, O’Keeffe’s Working Hands delivers real relief and lasting repair. It’s made for hardworking people who need hands that feel strong, smooth, and protected, day after day. |
|
 |
Burt’s Bees Almond & Milk Hand Cream, 2 Oz |
This hand cream is perfect for anyone with dry, rough hands who wants long-lasting moisture from natural ingredients. Busy hands need gentle care—sweet almond oil and beeswax heal cracks without harsh chemicals. Use it daily for soft, comfortably smooth skin that lasts. |
Detailed Reviews
Discover the 10 best bedtime hand creams, chosen through expert analysis and real customer results. Each one is reviewed for overnight repair, safety, and visible improvement for dry, cracked skin. Trust this guide to match your needs—whether it’s deep healing or sensitive-skin care. Wake up to softer, stronger hands with these proven nighttime treatments.
1. O’Keeffe’s Working Hands Night Treatment Hand Cream for Extreme Dryness – 7 oz Tube (1 Pack) – Repairing Skincare for Cracked, Dry Hands
O’Keeffe’s Working Hands Night Treatment is a powerful hand cream for extremely dry, cracked hands. It works while you sleep to restore your skin. Wake up to softer, smoother hands in just one night.
This cream is made with deep conditioning oils and feels light, not greasy. It’s hypoallergenic and safe for everyone, even those with diabetes.
Use it after washing, bathing, or at bedtime for the best results. The 7-ounce tube is perfect for reliable at-home care. Get your hands back overnight with this trusted treatment.
| Pros | Cons |
|---|---|
|
|
Perfect For:
O'Keeffe's Working Hands Night Treatment is perfect for anyone whose hands are cracked, raw, or painfully dry—especially nurses, dishwashers, mechanics, gardeners, and frequent hand-washers.
If you wake up with stiff, sore hands that feel worse in the morning, this cream works while you sleep to repair and soften skin overnight. It’s made for people who need real relief, not just temporary moisture.
Ready to Purchase?
2. O’Keeffe’s Working Hands Hand Cream for Extreme Dryness – 3 oz Travel Size Tube (1 Pack) – Repairing Skincare for Cracked, Dry Hands
Cracked hands? Meet your fix. O’Keeffe’s Working Hands Hand Cream targets extreme dryness fast. It’s the #1 brand in America for a reason—relief that lasts.
This concentrated cream locks in moisture with a protective barrier. It soothes pain and visibly repairs cracked skin within days. Just apply after washing or at bedtime for serious results.
Safe for sensitive skin and diabetes-friendly—no scent, no greasy residue. The 3 oz tube slips into any pocket or bag. Comfort travels with you, anywhere, anytime.
| Pros | Cons |
|---|---|
|
|
Perfect For:
This hand cream is perfect for anyone whose hands are rough, cracked, or painfully dry—especially nurses, construction workers, mechanics, gardeners, and frequent hand-washers. If your skin feels tight, looks flaky, or stings after work, O’Keeffe’s Working Hands delivers real relief when regular lotions just won’t cut it.
Keep it with you at work, in your gym bag, or by your bed—one dab transforms dry, raw skin into smooth, strong hands you can rely on.
Ready to Purchase?
3. Aveda Hand Relief Moisturizing Creme | Rich Hand Cream | with Andiroba Oil, 1.3 Fl Oz
Dry, cracked hands? Meet your match. Aveda Hand Relief Moisturizing Creme delivers instant comfort with rich, lasting hydration that truly works.
95% naturally derived ingredients power this formula. Andiroba oil deeply nourishes while plant-based hydrators lock in softness all day long.
Use anytime, anywhere—it absorbs fast without greasy residue. Restore smooth, healthy hands with just one swipe. Your best skin starts now.
| Pros | Cons |
|---|---|
|
|
Perfect For:
Dry, cracked hands? This cream is perfect for you.
Hardworking hands that wash often, face cold weather, or just need deep comfort—feel softer fast.
Anyone craving lasting hydration with clean, naturally derived ingredients will love it.
Vegan, cruelty-free, and mindful—ideal for those who care what touches their skin.
Reaches for hand cream all day? Rejoice—relief that lasts is finally here.
Ready to Purchase?
4. O’Keeffe’s Working Hands Hand Cream for Extreme Dryness – 3.4 oz Jar (1 Pack) – Repairing Skincare for Cracked, Dry Hands
Cracked, dry hands? O'Keeffe's Working Hands heals them fast. This concentrated cream locks in moisture like a shield, delivering real relief for skin that's been through the wringer.
It works instantly. You feel the difference right away. Safe for sensitive skin and people with diabetes, it's unscented, non-greasy, and seriously effective.
Apply after washing, bathing, or before bed. That 3.4 oz jar goes everywhere with you. Trust the #1 hand cream brand in America to restore your hands—strong, smooth, and ready to work.
| Pros | Cons |
|---|---|
|
|
Perfect For:
O'Keeffe's Working Hands Hand Cream is perfect for anyone whose hands crack, bleed, or feel raw from hard work, harsh weather, or constant washing—think nurses, mechanics, farmers, chefs, and busy parents. If your skin feels like sandpaper, this cream locks in moisture to heal and protect, so you get real relief, fast.
Ready to Purchase?
5. L’Occitane Nourishing Lavender Hand Cream Enriched with Lavender Essential Oil and Shea Butter, Net Wt. 1 oz.
Silky soft hands, anytime. This hand cream sinks in fast to nourish dry skin with real lavender oil and shea butter—no greasy residue, just lasting comfort. One dab and feel the difference.
It helps nourish and soften hands in seconds. Your skin stays hydrated and protected through washing and daily use. Smooth, healthy hands are just a pump away.
Lightweight, non-sticky, and perfect for your bag or desk. Lavender’s calming scent makes every application a small luxury. Hydrated skin feels better—plain and simple.
| Pros | Cons |
|---|---|
|
|
Perfect For:
This hand cream is perfect for anyone with dry or tired hands who wants quick relief. If your skin feels rough or tight after washing, it needs this soothing blend of lavender oil and shea butter. Use it daily to keep hands soft and protected, even in harsh weather. Busy hands deserve care—apply a little and feel the difference right away. Ideal for nurses, teachers, cooks, and parents who wash hands often and need lasting comfort. Gentle, effective, and deeply nourishing without greasiness.
Ready to Purchase?
6. O’Keeffe’s Working Hands Hand Cream for Extreme Dryness – 3 oz Tube (2 Pack) – Repairing Skincare for Cracked, Dry Hands
Cracked hands? Meet your match. O’Keeffe’s Working Hands locks in moisture like armor for severely dry, cracked skin. Works overnight to heal raw, painful hands fast.
Guaranteed relief from extreme dryness—no fragrance, no grease, just deep repair. Safe for sensitive skin and diabetes. Keep a tube by your sink and your nightstand. Apply after hand washing and before bedtime—dry hands need consistency to heal. Results you can feel and see: nourished, strong, comfortable skin again.
| Pros | Cons |
|---|---|
|
|
Perfect For:
O'Keeffe's Working Hands Hand Cream is perfect for anyone whose hands are rough, cracked, or painfully dry from hard work, frequent washing, or harsh weather. If you wash dishes, work outdoors, use tools, or spend hours with your hands in water or sanitizer, this cream delivers real relief fast. It’s especially trusted by nurses, mechanics, cleaners, gardeners, and builders who need their hands to feel strong again. Safe, unscented, and non-greasy, it fits right into your daily routine—guaranteed to heal what everyday life breaks.
Ready to Purchase?
7. eos Shea Better Hand Cream – Vanilla Cashmere Hand Lotion | Instant Hydration + Lasting Protection | 2.5 oz
Smooth, fast-absorbing relief for dry hands. Just glide it on after washing—no greasy residue, just soft skin and a warm vanilla-cashmere scent that lingers pleasantly.
Shea butter and nourishing oils lock in moisture for a full 24 hours, even through hand washes. This vegan, hypoallergenic formula is dermatologist-tested and Leaping Bunny certified—safe, sustainable, and truly kind to your skin.
| Pros | Cons |
|---|---|
|
|
Perfect For:
This hand cream is perfect for anyone with dry, rough hands who wants fast relief and lasting softness. If you wash your hands often or work in tough conditions, Vanilla Cashmere delivers instant hydration and 24-hour protection without grease or residue. Vegan and hypoallergenic, it’s safe for sensitive skin and packed with nourishing shea butter and oils. Whether you’re a busy nurse, a parent juggling chores, or just someone who hates dry patches, this travel-size lotion fits right into your daily routine—smooth, soothing, and seriously effective. Pamper your hands the clean, kind way: apply, feel better, repeat.
Ready to Purchase?
8. No7 Protect & Perfect Intense Advanced Nourishing Hand and Nail Cream – Anti Aging Hand Cream with Vitamin B5 – Contains Matrixyl 3000+ Collagen Peptide Anti Wrinkle Technology (75 ml)
Say goodbye to dry, aging hands. This fast-absorbing hand cream delivers instant moisture while working deep down to rebuild skin’s youthful look—thanks to Pro-Retinol and Matrixyl 3000+, proven anti-aging actives that smooth fine lines and firm skin.
Vitamin B5 deeply nourishes cuticles and nails, leaving hands soft, strong, and visibly rejuvenated in just two weeks. It’s more than hydration—it’s real results for healthier-looking hands. No gimmicks, just science-backed care you can trust. Discover the difference with No7.
| Pros | Cons |
|---|---|
|
|
Perfect For:
This hand cream is perfect for women who want younger-looking hands without heavy effort. If your skin feels dry or shows fine lines, it deeply moisturizes and smooths quickly. Busy moms, professionals, and skincare lovers will love how fast it absorbs and how real the results look—no greasy residue, just soft, firmer skin. Make it your daily shield against aging hands, especially if you use sanitizers often or work with your hands. Trust No7 to deliver visible improvement in just two weeks.
Ready to Purchase?
9. O’Keeffe’s Working Hands Hand Cream for Extreme Dryness – 7 oz Tube (1 Pack) – Repairing Skincare for Cracked, Dry Hands
Cracked hands? Meet your match. O’Keeffe’s Working Hands cream goes deep to heal dry, damaged skin fast. It locks in moisture where you need it most.
Guaranteed relief for extreme dryness creates a protective shield that keeps working all day. Apply after washing or at bedtime for maximum repair.
Safe for sensitive skin—unscented, non-greasy, and trusted by those with diabetes. One 7 oz tube gives your hardworking hands lasting comfort and real results.
| Pros | Cons |
|---|---|
|
|
Perfect For:
This hand cream is perfect for anyone whose hands are rough, cracked, or painfully dry. If you wash your hands constantly, work with tools, chemicals, or outdoors, or just can’t seem to heal dry skin no matter what you try, O’Keeffe’s Working Hands delivers real relief and lasting repair. It’s made for hardworking people who need hands that feel strong, smooth, and protected, day after day.
Ready to Purchase?
10. Burt’s Bees Almond & Milk Hand Cream, 2 Oz
Dry, cracked hands? Not anymore. Burt’s Bees Almond & Milk Hand Cream delivers 24-hour hydration with 99% natural ingredients. It’s a simple, powerful solution for hands that work hard.
Sweet almond oil and vitamin E deeply nourish rough skin while beeswax locks in moisture. This fast-absorbing cream softens elbows, knees, and feet without greasy residue. You’ll feel relief almost instantly.
The gentle nutty almond scent calms your senses, never overwhelming. Free from phthalates, parabens, and petrolatum, it’s clean care you can trust every day. Give your hands the natural comfort they deserve.
| Pros | Cons |
|---|---|
|
|
Perfect For:
This hand cream is perfect for anyone with dry, rough hands who wants long-lasting moisture from natural ingredients. Busy hands need gentle care—sweet almond oil and beeswax heal cracks without harsh chemicals. Use it daily for soft, comfortably smooth skin that lasts.
Ready to Purchase?
Buying Guide
Dry, cracked hands hurt at night and slow healing. The right bedtime hand cream works while you sleep to rebuild skin. Wake up feeling real softness with less pain and fewer cracks.
People massage it in before bed and trust it fast. After just a few nights, skin looks and feels repaired. That relief builds confidence—your hands finally heal when you rest.
Let this guide help you choose the perfect night cream for your hands. You’ll find clear, proven options that repair as you rest. Ready for smoother mornings? Let’s begin.
-
Factor: Intense Repair for Cracked Skin
Choose creams made for extreme dryness or cracks. These formulas go deep to heal damage, not just sit on top. O’Keeffe’s creates a protective shield that restores skin overnight. -
Factor: Absorbs Fast, Non-Greasy Feel
You want a cream that soaks in quickly without sticky residue. Light, not greasy textures let you sleep easy. Aveda and eos absorb fast so you don’t toss and turn. -
Factor: Safe for Sensitive or Diabetic Skin
Look for hypoallergenic, fragrance-free options if skin is easily irritated. O’Keeffe’s and Burt’s Bees avoid harsh additives. They’re safe for everyone, even with diabetes. -
Factor: Natural and Nourishing Ingredients
Plant-based oils, shea butter, and vitamin E feed skin gently. Burt’s Bees uses 99% natural ingredients. Aveda relies on 95% naturally derived power for lasting softness. -
Factor: Proven Results You Can Feel
Pick creams backed by real user experience. Many wake with less pain and visible repair after just one night. Trust builds when results last through hand washing and daily wear. -
Factor: Size and Value for Daily Use
A larger tube (7 oz) lasts at home. Travel sizes (3 oz or 2.5 oz) go in bags or pockets. Buying a 2-pack saves money for regular, reliable care. -
Factor: Pleasant Scent or Fragrance-Free
Some like a calming lavender scent or warm vanilla. Others need unscented for sensitivity. L’Occitane and eos add light fragrance; O’Keeffe’s stays neutral. -
Factor: Multi-Task or Hand-Only Focus
Most hand creams also smooth elbows, knees, or cuticles. Check labels if you want extra use. Burt’s Bees and Aveda work well beyond just hands. -
Factor: Science-Backed Anti-Aging Help
If you want younger-looking skin, look for collagen peptides or pro-retinol. No7 uses Matrixyl 3000+ to rebuild firmness and fade lines in two weeks. -
Factor: Easy Application Routine
Apply after washing hands or before bed. Keep it by the sink or nightstand so you never skip. Consistency heals cracked skin best—use it nightly.
Each cream here delivers real comfort while you sleep. Your hands deserve repair that works overnight—strong, soft, and ready. Choose what fits your skin, your life, and your need for relief you can trust.